Periodontal diseases are a diverse group of infectious diseases of periodontal tissues with different specific pathogens, which are non-clostridial anaerobic bacteria. According to the WHO classification, they are grouped in the so-called Periodontopathogenic Bacteria (PB).

It is now established that this group of pathogens is a major cause of progressive periodontal disease. This leads to the need for specific methods of diagnosis and treatment of identified bacteria in chronic-progressive-resistant and aggressive periodontal disease. Purely mechanical treatment is generally ineffective, particularly when PB are present in oral cavity and in this case it should be used antibacterial therapy. A necessary condition for choosing the appropriate antimicrobial agent is the knowledge of the bacterial spectrum and the concentration of present microorganisms.